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| navigate by keyword : gout tophus urate crystals needle birefringent inflammation macrophages histology pathology photomicrograph microscopy micrograph slide tissue arthritis joint deposit monosodium crystal immune reaction chronic granuloma giant cells neutrophils eosinophils pain swelling nodules diagnosis polarizing birefringence soft skin synovium histopathology sample stained eosin hematoxylin cellular tophi lesion uric acid inflammatory |
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| Gout tophus, photomicrograph showing amorphous, eosinophilic material with a foreign-body giant cell reaction and inflammation. |
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