microangiopathic |
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| navigate by keyword : thrombotic thrombocytopenic purpura ttp pathophysiology adamts13 deficiency von willebrand factor multimers platelet microthrombi microangiopathic hemolytic anemia schistocytes thrombocytopenia hemolysis endothelial injury red blood cell fragmentation aggregation vessel clot formation hemostasis plasma exchange autoantibodies neurologic symptoms renal failure fever pentad microthrombus vwf cleavage hematology infographic chart disease mechanism |
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| TTP pathophysiology illustrated, ADAMTS13 deficiency leads to ultra-large vWF, platelet-rich microthrombi in a blood vessel, key items are platelets, RBCs, microthrombus. Outline diagram |
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