jak |
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| navigate by keyword : jak stat pathway signaling cytokine receptor kinase transcription factor dimerization tyrosine phosphorylation ligand binding activation signal transduction nuclear translocation gene cell membrane intracellular immune interferon interleukin prolactin gp130 cascade regulation targeted therapy inhibitor inflammation oncogenic hematopoiesis biomedical diagram molecular systems biology |
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| JAK-STAT cell signaling, ligand binds receptor, JAK activates, STAT dimer enters nucleus to drive transcription. Key objects, receptor, ligand, STAT. |
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