melanocortin
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melanocortin |
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| navigate by keyword : 2021 6r3q 7aue activation adenylyl agonist antigen antiobesity appetite atp binding blood bodyweight brain camp cascade cell central control coupled crucial cylclase defense drug energy entries gtp homeostasis immune immunization israeli leads lymphocyte melacortin melanocortin membrane molecules nervous obesity overweight pathway pdb protein receptor science setmelatonide signal signaling source system transduction white |
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| The melanocortin receptor 4 is crucial for appetite, energy homeostasis and body-weight control in the central nervous system. Binding of the agonist setmelatonide to the melacortin receptor leads to a G-protein coupled C-AMP signaling pathway. Source: PDB entries 7aue, 6r3q,. Israeli, H. et al. 2021 Science |
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